SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB03090

Signal sequence   MLKKCLPLLLLCTAPVFA

Length  18

Organism  Escherichia coli (strain K12)

UniProt ID  P31550,

Motif  1..18



Activity Information


Pathway  Sec

Natural/Artificial  Natural

Subcellular location  Periplasmic space

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB03090.cif

Structure  SPKB03090.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  1974.59534

Aliphatic index  157.2222222

Isoelectric point  8.821677593

Charge (pH=7)   1.8734448

Topological polar surface area  612.71

Aromaticity  0.055555556

Average rotatable bonds  3.444444444

Number of hydrogen bond donors  22

Number of hydrogen bond acceptors  25

X logP energy  0.1189

Hydropathy 



Literature Information


Title  Overexpression, purification, and characterization of the periplasmic space thiamin-binding protein of the thiamin traffic ATPase in Escherichia coli.

DOI  10.1016/s1046-5928(02)00031-1,

Publication Year  2002

PubMed ID  12182833,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.