SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB03089

Signal sequence   MLNERIQPGMIFLLTVSLCHFMEYRAVQA

Length  29

Organism  Xenopus laevis (African clawed frog)

UniProt ID  P31515,

Motif  1..29



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB03089.cif

Structure  SPKB03089.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  3412.10444

Aliphatic index  107.5862069

Isoelectric point  7.357622758

Charge (pH=7)   0.029611883

Topological polar surface area  1286.37

Aromaticity  0.103448276

Average rotatable bonds  3.862068966

Number of hydrogen bond donors  45

Number of hydrogen bond acceptors  45

X logP energy  -7.63706

Hydropathy 



Literature Information


Title  Isolation and characterization of Xenopus follistatin and activins.

DOI  10.1006/dbio.1993.1227,

Publication Year  1993

PubMed ID  8365557,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.