SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB03088

Signal sequence   MWTSWWLWPLVAVCTA

Length  16

Organism  Oryctolagus cuniculus (Rabbit)

UniProt ID  P31429,

Motif  1..16



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB03088.cif

Structure  SPKB03088.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  1950.34614

Aliphatic index  97.5

Isoelectric point  5.922539791

Charge (pH=7)   -0.063990417

Topological polar surface area  614.88

Aromaticity  0.25

Average rotatable bonds  3.1875

Number of hydrogen bond donors  24

Number of hydrogen bond acceptors  22

X logP energy  0.9533

Hydropathy 



Literature Information


Title  Cloning of cDNAs encoding a rabbit renal brush border membrane protein immunologically related to band 3. Sequence similarity with microsomal dipeptidase.

DOI  10.1042/bj2800071,

Publication Year  1991

PubMed ID  1741759,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.