SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB03074

Signal sequence   MAPPTRQLLNAVLVLLLLLATNHQGTGVVVA

Length  31

Organism  Rattus norvegicus (Rat)

UniProt ID  P30348,

Motif  1..31



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB03074.cif

Structure  SPKB03074.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  3223.91134

Aliphatic index  160.3225806

Isoelectric point  10.5517587

Charge (pH=7)   1.088890079

Topological polar surface area  1242.37

Aromaticity  0

Average rotatable bonds  3.290322581

Number of hydrogen bond donors  41

Number of hydrogen bond acceptors  42

X logP energy  -9.64773

Hydropathy 



Literature Information


Title  Identification of cytokine-induced neutrophil chemoattractants (CINC), rat GRO/CINC-2 alpha and CINC-2 beta, produced by granulation tissue in culture: purification, complete amino acid sequences and characterization.

DOI  10.1042/bj3010545,

Publication Year  1994

PubMed ID  8043001,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.