SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB03071

Signal sequence   MGAAARSLRLALGLLLLATLLRPADA

Length  26

Organism  Rattus norvegicus (Rat)

UniProt ID  P30121,

Motif  1..26



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB03071.cif

Structure  SPKB03071.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2648.24894

Aliphatic index  161.9230769

Isoelectric point  12.19913391

Charge (pH=7)   1.99842085

Topological polar surface area  1045.49

Aromaticity  0

Average rotatable bonds  3.346153846

Number of hydrogen bond donors  38

Number of hydrogen bond acceptors  34

X logP energy  -7.76779

Hydropathy 



Literature Information


Title  Purification and sequence analysis of two rat tissue inhibitors of metalloproteinases.

DOI  10.1016/0003-9861(92)90009-l,

Publication Year  1992

PubMed ID  1309971,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.