SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB03070

Signal sequence   MAPFASLASGILLLLSLIASSKA

Length  23

Organism  Rattus norvegicus (Rat)

UniProt ID  P30120,

Motif  1..23



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB03070.cif

Structure  SPKB03070.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2274.78734

Aliphatic index  157.3913043

Isoelectric point  9.700002532

Charge (pH=7)   0.997689266

Topological polar surface area  821.9

Aromaticity  0.043478261

Average rotatable bonds  3.217391304

Number of hydrogen bond donors  29

Number of hydrogen bond acceptors  31

X logP energy  -6.2439

Hydropathy 



Literature Information


Title  Purification and sequence analysis of two rat tissue inhibitors of metalloproteinases.

DOI  10.1016/0003-9861(92)90009-l,

Publication Year  1992

PubMed ID  1309971,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.