SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB03069

Signal sequence   MRLRRLALFPGVALLLAAARLAAA

Length  24

Organism  Homo sapiens (Human)

UniProt ID  P30101,

Motif  1..24



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  7QNG,

Predicted Structure ID  SPKB03069.cif

Structure  SPKB03069.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2535.18184

Aliphatic index  159.1666667

Isoelectric point  12.97714556

Charge (pH=7)   3.997971054

Topological polar surface area  971.43

Aromaticity  0.041666667

Average rotatable bonds  3.416666667

Number of hydrogen bond donors  36

Number of hydrogen bond acceptors  30

X logP energy  -5.12692

Hydropathy 



Literature Information


Title  Exploring proteomes and analyzing protein processing by mass spectrometric identification of sorted N-terminal peptides.

DOI  10.1038/nbt810,

Publication Year  2003

PubMed ID  12665801,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.