General Information
SPKB ID SPKB03069
Signal sequence MRLRRLALFPGVALLLAAARLAAA
Length 24
Organism Homo sapiens (Human)
UniProt ID P30101,
Motif 1..24
Activity Information
Pathway SRP-dependent
Natural/Artificial Natural
Subcellular location ER
Secretion efficiency NA
Type Sec/SPI
Structure Information
PDB ID 7QNG,
Predicted Structure ID SPKB03069.cif
Physicochemical Information
Molecular weight 2535.18184
Aliphatic index 159.1666667
Isoelectric point 12.97714556
Charge (pH=7) 3.997971054
Topological polar surface area 971.43
Aromaticity 0.041666667
Average rotatable bonds 3.416666667
Number of hydrogen bond donors 36
Number of hydrogen bond acceptors 30
X logP energy -5.12692
Hydropathy
Literature Information
Title Exploring proteomes and analyzing protein processing by mass spectrometric identification of sorted N-terminal peptides.
DOI 10.1038/nbt810,
Publication Year 2003
PubMed ID 12665801,
Patent ID NA,