SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB03068

Signal sequence   MAAAVPRAAFLSPLLPLLLGFLLLSAPHGGSG

Length  32

Organism  Homo sapiens (Human)

UniProt ID  P30040,

Motif  1..32



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB03068.cif

Structure  SPKB03068.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  3158.83864

Aliphatic index  137.5

Isoelectric point  10.5517587

Charge (pH=7)   1.088890079

Topological polar surface area  1081.53

Aromaticity  0.0625

Average rotatable bonds  2.9375

Number of hydrogen bond donors  36

Number of hydrogen bond acceptors  39

X logP energy  -6.38773

Hydropathy 



Literature Information


Title  Human liver protein map: update 1993.

DOI  10.1002/elps.11501401181,

Publication Year  1993

PubMed ID  8313870,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.