SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB03066

Signal sequence   MKSIYFVAGLFVMLVQGSWQ

Length  20

Organism  Canis lupus familiaris (Dog) (Canis familiaris)

UniProt ID  P29794,

Motif  1..20



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB03066.cif

Structure  SPKB03066.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2304.79334

Aliphatic index  107

Isoelectric point  9.298300651

Charge (pH=7)   0.996838851

Topological polar surface area  804.9

Aromaticity  0.2

Average rotatable bonds  3.7

Number of hydrogen bond donors  28

Number of hydrogen bond acceptors  29

X logP energy  -2.693

Hydropathy 



Literature Information


Title  Immunoreactive glucagons purified from dog pancreas, stomach and ileum.

DOI  10.1016/0167-0115(88)90230-3,

Publication Year  1988

PubMed ID  3238052,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.