SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB03064

Signal sequence   MNSLVALVLLGQIIGSTLS

Length  19

Organism  Protobothrops flavoviridis (Habu) (Trimeresurus flavoviridis)

UniProt ID  P29695,

Motif  1..19



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB03064.cif

Structure  SPKB03064.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  1929.34564

Aliphatic index  179.4736842

Isoelectric point  6.099999998

Charge (pH=7)   -0.002015701

Topological polar surface area  754.22

Aromaticity  0

Average rotatable bonds  3.421052632

Number of hydrogen bond donors  26

Number of hydrogen bond acceptors  27

X logP energy  -6.7062

Hydropathy 



Literature Information


Title  Primary structure of the antihemorrhagic factor in serum of the Japanese Habu: a snake venom metalloproteinase inhibitor with a double-headed cystatin domain.

DOI  10.1093/oxfordjournals.jbchem.a123944,

Publication Year  1992

PubMed ID  1478916,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.