SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB03060

Signal sequence   MDCQLSILLLLSCSVLDSFG

Length  20

Organism  Homo sapiens (Human)

UniProt ID  P29320,

Motif  1..20



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB03060.cif

Structure  SPKB03060.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2157.58304

Aliphatic index  151

Isoelectric point  3.491868389

Charge (pH=7)   -2.125072164

Topological polar surface area  814.83

Aromaticity  0.05

Average rotatable bonds  3.6

Number of hydrogen bond donors  30

Number of hydrogen bond acceptors  31

X logP energy  -6.7409

Hydropathy 



Literature Information


Title  Isolation and characterization of a novel receptor-type protein tyrosine kinase (hek) from a human pre-B cell line.

DOI  NA,

Publication Year  1992

PubMed ID  1737782,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.