SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB03059

Signal sequence   MDTWMVLLGLQILLLPLLAHCT

Length  22

Organism  Rattus norvegicus (Rat)

UniProt ID  P29288,

Motif  1..22



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  1QHW,

Predicted Structure ID  SPKB03059.cif

Structure  SPKB03059.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2495.13764

Aliphatic index  177.2727273

Isoelectric point  5.289877379

Charge (pH=7)   -0.972634841

Topological polar surface area  830.95

Aromaticity  0.045454545

Average rotatable bonds  3.590909091

Number of hydrogen bond donors  29

Number of hydrogen bond acceptors  31

X logP energy  -0.5649

Hydropathy 



Literature Information


Title  Characterization of a tartrate-resistant acid phosphatase (ATPase) from rat bone: hydrodynamic properties and N-terminal amino acid sequence.

DOI  10.1002/jbmr.5650060408,

Publication Year  1991

PubMed ID  1830446,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.