SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB03058

Signal sequence   MSPVAIIACVCLAVTLTSISPSEA

Length  24

Organism  Aplysia californica (California sea hare)

UniProt ID  P29241,

Motif  1..24



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB03058.cif

Structure  SPKB03058.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2376.86734

Aliphatic index  134.1666667

Isoelectric point  3.849941048

Charge (pH=7)   -1.12419001

Topological polar surface area  873.72

Aromaticity  0

Average rotatable bonds  3

Number of hydrogen bond donors  32

Number of hydrogen bond acceptors  35

X logP energy  -8.9525

Hydropathy 



Literature Information


Title  Unifying mechanism for Aplysia ADP-ribosyl cyclase and CD38/NAD(+) glycohydrolases.

DOI  10.1042/0264-6021:3490203,

Publication Year  2000

PubMed ID  10861229,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.