SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB03049

Signal sequence   MWTLVGWTILVAGLVAG

Length  17

Organism  Cavia porcellus (Guinea pig)

UniProt ID  P28797,

Motif  1..17



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB03049.cif

Structure  SPKB03049.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  1787.19314

Aliphatic index  154.7058824

Isoelectric point  6.099999998

Charge (pH=7)   -0.002015701

Topological polar surface area  600.96

Aromaticity  0.117647059

Average rotatable bonds  3.117647059

Number of hydrogen bond donors  22

Number of hydrogen bond acceptors  21

X logP energy  -0.7958

Hydropathy 



Literature Information


Title  Acrogranin, an acrosomal cysteine-rich glycoprotein, is the precursor of the growth-modulating peptides, granulins, and epithelins, and is expressed in somatic as well as male germ cells.

DOI  10.1002/mrd.1080340302,

Publication Year  1993

PubMed ID  8471244,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.