SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB03047

Signal sequence   MVKKSLRQFTLMATATVTLLLGSVPLYA

Length  28

Organism  Escherichia coli

UniProt ID  P28585,

Motif  1..28



Activity Information


Pathway  Sec

Natural/Artificial  Natural

Subcellular location  Extracellular environment

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  5T66,

Predicted Structure ID  SPKB03047.cif

Structure  SPKB03047.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  3053.75544

Aliphatic index  125.3571429

Isoelectric point  10.90180955

Charge (pH=7)   2.996540506

Topological polar surface area  1138.87

Aromaticity  0.071428571

Average rotatable bonds  3.571428571

Number of hydrogen bond donors  41

Number of hydrogen bond acceptors  42

X logP energy  -8.07843

Hydropathy 



Literature Information


Title  Close amino acid sequence relationship between the new plasmid-mediated extended-spectrum beta-lactamase MEN-1 and chromosomally encoded enzymes of Klebsiella oxytoca.

DOI  10.1016/0167-4838(92)90121-s,

Publication Year  1992

PubMed ID  1633193,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.