SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB03046

Signal sequence   MLLPVPLLLGLVGLAAA

Length  17

Organism  Sus scrofa (Pig)

UniProt ID  P28491,

Motif  1..17



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB03046.cif

Structure  SPKB03046.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  1661.16244

Aliphatic index  212.3529412

Isoelectric point  6.099999998

Charge (pH=7)   -0.002015701

Topological polar surface area  511.34

Aromaticity  0

Average rotatable bonds  2.941176471

Number of hydrogen bond donors  16

Number of hydrogen bond acceptors  19

X logP energy  0.8778

Hydropathy 



Literature Information


Title  Calreticulin, and not calsequestrin, is the major calcium binding protein of smooth muscle sarcoplasmic reticulum and liver endoplasmic reticulum.

DOI  NA,

Publication Year  1991

PubMed ID  2016321,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.