General Information
SPKB ID SPKB03045
Signal sequence MVNLRNAVHSFLVHLIGLLVWQSDISVSPVAA
Length 32
Organism Homo sapiens (Human)
UniProt ID P28335,
Motif 1..32
Activity Information
Pathway SRP-dependent
Natural/Artificial Natural
Subcellular location ER
Secretion efficiency NA
Type Sec/SPI
Structure Information
PDB ID NA,
Predicted Structure ID SPKB03045.cif
Physicochemical Information
Molecular weight 3487.12344
Aliphatic index 149.0625
Isoelectric point 7.714638646
Charge (pH=7) 0.180245654
Topological polar surface area 1339.17
Aromaticity 0.0625
Average rotatable bonds 3.4375
Number of hydrogen bond donors 46
Number of hydrogen bond acceptors 45
X logP energy -9.74203
Hydropathy 
Literature Information
Title The N-terminal region of the human 5-HT?C receptor has as a cleavable signal peptide.
DOI 10.1016/j.ejphar.2012.03.043,
Publication Year 2012
PubMed ID 22497996,
Patent ID NA,
