SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB03041

Signal sequence   MPRLPLLLLLLWGTGSHG

Length  18

Organism  Bos taurus (Bovine)

UniProt ID  P28053,

Motif  1..18



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB03041.cif

Structure  SPKB03041.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  1974.43784

Aliphatic index  151.6666667

Isoelectric point  10.5517587

Charge (pH=7)   1.088890079

Topological polar surface area  687.27

Aromaticity  0.055555556

Average rotatable bonds  3.333333333

Number of hydrogen bond donors  24

Number of hydrogen bond acceptors  24

X logP energy  -2.05153

Hydropathy 



Literature Information


Title  Purification and characterization of bovine interstitial collagenase and tissue inhibitor of metalloproteinases.

DOI  10.1016/0003-9861(92)90408-o,

Publication Year  1992

PubMed ID  1311165,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.