SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB03040

Signal sequence   MQSPWKILTVAPLFLLLSLQSSA

Length  23

Organism  Homo sapiens (Human)

UniProt ID  P28039,

Motif  1..23



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB03040.cif

Structure  SPKB03040.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2544.09044

Aliphatic index  140

Isoelectric point  9.700002532

Charge (pH=7)   0.997689266

Topological polar surface area  915.08

Aromaticity  0.086956522

Average rotatable bonds  3.47826087

Number of hydrogen bond donors  31

Number of hydrogen bond acceptors  33

X logP energy  -5.1754

Hydropathy 



Literature Information


Title  A saposin-like domain influences the intracellular localization, stability, and catalytic activity of human acyloxyacyl hydrolase.

DOI  NA,

Publication Year  1994

PubMed ID  8089145,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.