General Information
SPKB ID SPKB03037
Signal sequence MAFHSTLLVFLAGLVFLSEA
Length 20
Organism Gallus gallus (Chicken)
UniProt ID P27731,
Motif 1..20
Activity Information
Pathway SRP-dependent
Natural/Artificial Natural
Subcellular location ER
Secretion efficiency NA
Type Sec/SPI
Structure Information
PDB ID NA,
Predicted Structure ID SPKB03037.cif
Physicochemical Information
Molecular weight 2166.60624
Aliphatic index 141.5
Isoelectric point 5.363507222
Charge (pH=7) -0.909331487
Topological polar surface area 742.89
Aromaticity 0.15
Average rotatable bonds 3.4
Number of hydrogen bond donors 26
Number of hydrogen bond acceptors 27
X logP energy -2.4797
Hydropathy 
Literature Information
Title Isolation, characterization, cDNA cloning and gene expression of an avian transthyretin. Implications for the evolution of structure and function of transthyretin in vertebrates.
DOI 10.1111/j.1432-1033.1991.tb16232.x,
Publication Year 1991
PubMed ID 1833190,
Patent ID NA,
