SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB03036

Signal sequence   MLMLWTFAVLLGAVAG

Length  16

Organism  Rattus norvegicus (Rat)

UniProt ID  P27657,

Motif  1..16



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB03036.cif

Structure  SPKB03036.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  1693.13834

Aliphatic index  152.5

Isoelectric point  6.099999998

Charge (pH=7)   -0.002015701

Topological polar surface area  535.84

Aromaticity  0.125

Average rotatable bonds  3.25

Number of hydrogen bond donors  19

Number of hydrogen bond acceptors  20

X logP energy  0.3429

Hydropathy 



Literature Information


Title  Identification and cloning of GP-3 from rat pancreatic acinar zymogen granules as a glycosylated membrane-associated lipase.

DOI  NA,

Publication Year  1993

PubMed ID  8486693,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.