SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB03034

Signal sequence   MRARRGFILLLLLAVLCSTGVS

Length  22

Organism  Rattus norvegicus (Rat)

UniProt ID  P27274,

Motif  1..22



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB03034.cif

Structure  SPKB03034.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2389.98964

Aliphatic index  159.5454545

Isoelectric point  12.19926402

Charge (pH=7)   2.93599965

Topological polar surface area  920.81

Aromaticity  0.045454545

Average rotatable bonds  3.636363636

Number of hydrogen bond donors  36

Number of hydrogen bond acceptors  31

X logP energy  -6.40279

Hydropathy 



Literature Information


Title  Isolation and characterization of a membrane protein from rat erythrocytes which inhibits lysis by the membrane attack complex of rat complement.

DOI  10.1042/bj2840169,

Publication Year  1992

PubMed ID  1376109,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.