SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB03033

Signal sequence   MARLLTTCCLLALLLAACTDVALS

Length  24

Organism  Gallus gallus (Chicken)

UniProt ID  P27177,

Motif  1..24



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB03033.cif

Structure  SPKB03033.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2480.09564

Aliphatic index  162.9166667

Isoelectric point  5.997857946

Charge (pH=7)   -0.187496676

Topological polar surface area  912.74

Aromaticity  0

Average rotatable bonds  3.333333333

Number of hydrogen bond donors  36

Number of hydrogen bond acceptors  35

X logP energy  -6.91183

Hydropathy 



Literature Information


Title  A prion-like protein from chicken brain copurifies with an acetylcholine receptor-inducing activity.

DOI  10.1073/pnas.88.17.7664,

Publication Year  1991

PubMed ID  1715573,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.