SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB03032

Signal sequence   MTSKLAVAFLAVFLLSAALCEAAVL

Length  25

Organism  Sus scrofa (Pig)

UniProt ID  P26894,

Motif  1..25



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB03032.cif

Structure  SPKB03032.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2553.15674

Aliphatic index  156.4

Isoelectric point  6.231833229

Charge (pH=7)   -0.062510328

Topological polar surface area  885.73

Aromaticity  0.08

Average rotatable bonds  3.28

Number of hydrogen bond donors  32

Number of hydrogen bond acceptors  33

X logP energy  -4.0551

Hydropathy 



Literature Information


Title  Molecular cloning of porcine alveolar macrophage-derived neutrophil chemotactic factors I and II; identification of porcine IL-8 and another intercrine-alpha protein.

DOI  10.1021/bi00158a011,

Publication Year  1992

PubMed ID  1420165,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.