SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB03029

Signal sequence   MKKTFKLILVLMLSLTLVFGLTAPIQA

Length  27

Organism  Thermoanaerobacterium thermosulfurigenes (Clostridium thermosulfurogenes)

UniProt ID  P26827,

Motif  1..27



Activity Information


Pathway  Sec

Natural/Artificial  Natural

Subcellular location  Extracellular environment

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB03029.cif

Structure  SPKB03029.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2990.82614

Aliphatic index  158.8888889

Isoelectric point  11.10307074

Charge (pH=7)   2.997099198

Topological polar surface area  1013.2

Aromaticity  0.074074074

Average rotatable bonds  3.740740741

Number of hydrogen bond donors  35

Number of hydrogen bond acceptors  38

X logP energy  -2.3138

Hydropathy 



Literature Information


Title  alpha-Amylase of Clostridium thermosulfurogenes EM1: nucleotide sequence of the gene, processing of the enzyme, and comparison of other alpha-amylases.

DOI  10.1128/aem.57.5.1554-1559.1991,

Publication Year  1991

PubMed ID  1854207,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.