SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB03022

Signal sequence   MVRLPLQCVLWGCLLTAVHP

Length  20

Organism  Homo sapiens (Human)

UniProt ID  P25942,

Motif  1..20



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB03022.cif

Structure  SPKB03022.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2249.82194

Aliphatic index  146

Isoelectric point  8.242951845

Charge (pH=7)   0.964940647

Topological polar surface area  768.33

Aromaticity  0.05

Average rotatable bonds  3.35

Number of hydrogen bond donors  28

Number of hydrogen bond acceptors  28

X logP energy  -2.31623

Hydropathy 



Literature Information


Title  Determination of carbohydrate structures N-linked to soluble CD154 and characterization of the interactions of CD40 with CD154 expressed in Pichia pastoris and Chinese hamster ovary cells.

DOI  10.1006/prep.2001.1501,

Publication Year  2001

PubMed ID  11676606,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.