SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB03021

Signal sequence   MKLAACFLTLLPGFAVA

Length  17

Organism  Escherichia coli (strain K12)

UniProt ID  P25718,

Motif  1..17



Activity Information


Pathway  Sec

Natural/Artificial  Natural

Subcellular location  Periplasmic space

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  8IM8,

Predicted Structure ID  SPKB03021.cif

Structure  SPKB03021.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  1766.23304

Aliphatic index  132.3529412

Isoelectric point  8.545189979

Charge (pH=7)   0.93571455

Topological polar surface area  566.38

Aromaticity  0.117647059

Average rotatable bonds  3.176470588

Number of hydrogen bond donors  20

Number of hydrogen bond acceptors  22

X logP energy  -1.1092

Hydropathy 



Literature Information


Title  Molecular characterization of the MalT-dependent periplasmic alpha-amylase of Escherichia coli encoded by malS.

DOI  NA,

Publication Year  1992

PubMed ID  1544897,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.