General Information
SPKB ID SPKB03017
Signal sequence MGPRRLLLVAACFSLCGPLLS
Length 21
Organism Homo sapiens (Human)
UniProt ID P25116,
Motif 1..21
Activity Information
Pathway SRP-dependent
Natural/Artificial Natural
Subcellular location ER
Secretion efficiency NA
Type Sec/SPI
Structure Information
PDB ID NA,
Predicted Structure ID SPKB03017.cif
Physicochemical Information
Molecular weight 2217.77724
Aliphatic index 134.7619048
Isoelectric point 8.834915637
Charge (pH=7) 1.874028245
Topological polar surface area 792
Aromaticity 0.047619048
Average rotatable bonds 3.285714286
Number of hydrogen bond donors 30
Number of hydrogen bond acceptors 29
X logP energy -5.29156
Hydropathy
Literature Information
Title The protease-activated receptor 1 possesses a functional and cleavable signal peptide which is necessary for receptor expression.
DOI 10.1016/j.febslet.2012.05.042,
Publication Year 2012
PubMed ID 22659187,
Patent ID NA,