SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB03012

Signal sequence   MGAMTQLLAGVFLAFLALATEG

Length  22

Organism  Homo sapiens (Human)

UniProt ID  P24821,

Motif  1..22



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB03012.cif

Structure  SPKB03012.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2225.68934

Aliphatic index  124.5454545

Isoelectric point  3.849983241

Charge (pH=7)   -1.000240578

Topological polar surface area  795.27

Aromaticity  0.090909091

Average rotatable bonds  3.272727273

Number of hydrogen bond donors  27

Number of hydrogen bond acceptors  29

X logP energy  -4.6572

Hydropathy 



Literature Information


Title  Human tenascin: primary structure, pre-mRNA splicing patterns and localization of the epitopes recognized by two monoclonal antibodies.

DOI  10.1093/nar/19.3.525,

Publication Year  1991

PubMed ID  1707164,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.