SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB03009

Signal sequence   MKLFVPALLSLGALGLCLA

Length  19

Organism  Bos taurus (Bovine)

UniProt ID  P24627,

Motif  1..19



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB03009.cif

Structure  SPKB03009.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  1930.48084

Aliphatic index  174.7368421

Isoelectric point  8.545189979

Charge (pH=7)   0.93571455

Topological polar surface area  624.58

Aromaticity  0.052631579

Average rotatable bonds  3.263157895

Number of hydrogen bond donors  22

Number of hydrogen bond acceptors  24

X logP energy  -1.021

Hydropathy 



Literature Information


Title  Purification and characterization of bovine lactoferrin from secretions of the involuting mammary gland: identification of multiple molecular weight forms.

DOI  10.1016/0305-0491(89)90068-0,

Publication Year  1989

PubMed ID  2805645,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.