SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB03007

Signal sequence   MSSFTITVSFLLVLVFQFPGQTRA

Length  24

Organism  Sus scrofa (Pig)

UniProt ID  P24259,

Motif  1..24



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB03007.cif

Structure  SPKB03007.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2690.19584

Aliphatic index  105.4166667

Isoelectric point  10.55000222

Charge (pH=7)   0.997980988

Topological polar surface area  993.29

Aromaticity  0.166666667

Average rotatable bonds  3.5

Number of hydrogen bond donors  35

Number of hydrogen bond acceptors  35

X logP energy  -7.50393

Hydropathy 



Literature Information


Title  The auricular myocardiocytes of the heart constitute an endocrine organ. Characterization of a porcine cardiac peptide hormone, cardiodilatin-126.

DOI  10.1007/BF00219856,

Publication Year  1984

PubMed ID  6549270,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.