SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB03006

Signal sequence   MRFSRFIIGLTSCIAFSVQA

Length  20

Organism  Escherichia coli (strain K12)

UniProt ID  P24228,

Motif  1..20



Activity Information


Pathway  Sec

Natural/Artificial  Natural

Subcellular location  Periplasmic space

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB03006.cif

Structure  SPKB03006.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2247.70154

Aliphatic index  102.5

Isoelectric point  10.52640717

Charge (pH=7)   1.936002961

Topological polar surface area  864.03

Aromaticity  0.15

Average rotatable bonds  3.65

Number of hydrogen bond donors  33

Number of hydrogen bond acceptors  30

X logP energy  -7.31816

Hydropathy 



Literature Information


Title  Penicillin-binding protein 4 of Escherichia coli shows a novel type of primary structure among penicillin-interacting proteins.

DOI  10.1016/0378-1097(91)90160-c,

Publication Year  1991

PubMed ID  2040429,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.