SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB03003

Signal sequence   MSFRIAGPRLLLLGLQLFAKAWS

Length  23

Organism  Mus musculus (Mouse)

UniProt ID  P24063,

Motif  1..23



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB03003.cif

Structure  SPKB03003.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2589.18314

Aliphatic index  131.7391304

Isoelectric point  12.51647815

Charge (pH=7)   2.997682643

Topological polar surface area  943.89

Aromaticity  0.130434783

Average rotatable bonds  3.652173913

Number of hydrogen bond donors  34

Number of hydrogen bond acceptors  31

X logP energy  -3.91656

Hydropathy 



Literature Information


Title  Sequence homology of the LFA-1 and Mac-1 leukocyte adhesion glycoproteins and unexpected relation to leukocyte interferon.

DOI  10.1038/314540a0,

Publication Year  1985

PubMed ID  3887182,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.