SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB03001

Signal sequence   MRALWIVAVLLVGVEG

Length  16

Organism  Crotalus durissus terrificus (South American rattlesnake)

UniProt ID  P24027,

Motif  1..16



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB03001.cif

Structure  SPKB03001.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  1726.15344

Aliphatic index  182.5

Isoelectric point  6.410149741

Charge (pH=7)   -0.000243889

Topological polar surface area  614.81

Aromaticity  0.0625

Average rotatable bonds  3.4375

Number of hydrogen bond donors  22

Number of hydrogen bond acceptors  20

X logP energy  -0.61353

Hydropathy 



Literature Information


Title  Molecular evolution and structure-function relationships of crotoxin-like and asparagine-6-containing phospholipases A2 in pit viper venoms.

DOI  10.1042/BJ20040125,

Publication Year  2004

PubMed ID  15032748,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.