SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB02998

Signal sequence   MRISLKKSGMLKLGLSLVAMTVAASVQA

Length  28

Organism  Escherichia coli (strain K12)

UniProt ID  P23847,

Motif  1..28



Activity Information


Pathway  Sec

Natural/Artificial  Natural

Subcellular location  Periplasmic space

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  8Z1Y,

Predicted Structure ID  SPKB02998.cif

Structure  SPKB02998.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2904.62464

Aliphatic index  128.9285714

Isoelectric point  11.92450937

Charge (pH=7)   3.997095887

Topological polar surface area  1133.22

Aromaticity  0

Average rotatable bonds  3.678571429

Number of hydrogen bond donors  41

Number of hydrogen bond acceptors  42

X logP energy  -10.40003

Hydropathy 



Literature Information


Title  Peptide transport and chemotaxis in Escherichia coli and Salmonella typhimurium: characterization of the dipeptide permease (Dpp) and the dipeptide-binding protein.

DOI  10.1111/j.1365-2958.1991.tb01876.x,

Publication Year  1991

PubMed ID  1956284,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.