General Information
SPKB ID SPKB02996
Signal sequence MKTILPAVLFAAFATTSAWA
Length 20
Organism Escherichia coli (strain K12)
UniProt ID P23827,
Motif 1..20
Activity Information
Pathway Sec
Natural/Artificial Natural
Subcellular location Periplasmic space
Secretion efficiency NA
Type Sec/SPI
Structure Information
PDB ID 7CBK,
Predicted Structure ID SPKB02996.cif
Physicochemical Information
Molecular weight 2110.54214
Aliphatic index 103
Isoelectric point 9.700002532
Charge (pH=7) 0.997689266
Topological polar surface area 730.16
Aromaticity 0.15
Average rotatable bonds 3.1
Number of hydrogen bond donors 26
Number of hydrogen bond acceptors 27
X logP energy -3.7444
Hydropathy
Literature Information
Title The sequence and reactive site of ecotin. A general inhibitor of pancreatic serine proteases from Escherichia coli.
DOI NA,
Publication Year 1991
PubMed ID 2007606,
Patent ID NA,