SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB02995

Signal sequence   MGRFIFMSFGFLVVFLSLSGTAA

Length  23

Organism  Protobothrops flavoviridis (Habu) (Trimeresurus flavoviridis)

UniProt ID  P23807,

Motif  1..23



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB02995.cif

Structure  SPKB02995.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2499.02674

Aliphatic index  101.7391304

Isoelectric point  10.55000222

Charge (pH=7)   0.997980988

Topological polar surface area  846.34

Aromaticity  0.217391304

Average rotatable bonds  3.434782609

Number of hydrogen bond donors  31

Number of hydrogen bond acceptors  31

X logP energy  -4.16503

Hydropathy 



Literature Information


Title  The primary structure of coagulation factor IX/factor X-binding protein isolated from the venom of Trimeresurus flavoviridis. Homology with asialoglycoprotein receptors, proteoglycan core protein, tetranectin, and lymphocyte Fc epsilon receptor for immunoglobulin E.

DOI  NA,

Publication Year  1991

PubMed ID  1831197,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.