SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB02992

Signal sequence   MEYQILKMSLCLFILLFLTPGILC

Length  24

Organism  Homo sapiens (Human)

UniProt ID  P23515,

Motif  1..24



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB02992.cif

Structure  SPKB02992.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2803.57344

Aliphatic index  162.5

Isoelectric point  6.133393515

Charge (pH=7)   -0.125335458

Topological polar surface area  890.93

Aromaticity  0.125

Average rotatable bonds  3.833333333

Number of hydrogen bond donors  32

Number of hydrogen bond acceptors  35

X logP energy  0.5792

Hydropathy 



Literature Information


Title  A phosphatidylinositol-linked peanut agglutinin-binding glycoprotein in central nervous system myelin and on oligodendrocytes.

DOI  10.1083/jcb.106.4.1273,

Publication Year  1988

PubMed ID  3283151,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.