General Information
SPKB ID SPKB02988
Signal sequence MAAAGQLCLLYLSAGLLSRLGAA
Length 23
Organism Homo sapiens (Human)
UniProt ID P23229,
Motif 1..23
Activity Information
Pathway SRP-dependent
Natural/Artificial Natural
Subcellular location ER
Secretion efficiency NA
Type Sec/SPI
Structure Information
PDB ID NA,
Predicted Structure ID SPKB02988.cif
Physicochemical Information
Molecular weight 2263.74154
Aliphatic index 144.7826087
Isoelectric point 8.527213491
Charge (pH=7) 0.935155858
Topological polar surface area 869.2
Aromaticity 0.043478261
Average rotatable bonds 3.217391304
Number of hydrogen bond donors 32
Number of hydrogen bond acceptors 31
X logP energy -7.45523
Hydropathy 
Literature Information
Title Separation of important new platelet glycoproteins (GPIa, GPIc, GPIc*, GPIIa and GMP-140) by f.p.l.c. Characterization by monoclonal antibodies and gas-phase sequencing.
DOI 10.1042/bj2790419,
Publication Year 1991
PubMed ID 1953640,
Patent ID NA,
