SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB02987

Signal sequence   MERAAPSRRVPLPLLLLGGLALLAAGVDA

Length  29

Organism  Homo sapiens (Human)

UniProt ID  P23142,

Motif  1..29



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB02987.cif

Structure  SPKB02987.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2941.57164

Aliphatic index  148.2758621

Isoelectric point  10.30863985

Charge (pH=7)   1.000195972

Topological polar surface area  1132.28

Aromaticity  0

Average rotatable bonds  3.206896552

Number of hydrogen bond donors  39

Number of hydrogen bond acceptors  37

X logP energy  -7.93959

Hydropathy 



Literature Information


Title  Fibulin, a novel protein that interacts with the fibronectin receptor beta subunit cytoplasmic domain.

DOI  10.1016/0092-8674(89)90097-4,

Publication Year  1989

PubMed ID  2527614,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.