General Information
SPKB ID SPKB02986
Signal sequence MWLRAFILATLSASAAW
Length 17
Organism Homo sapiens (Human)
UniProt ID P23141,
Motif 1..17
Activity Information
Pathway SRP-dependent
Natural/Artificial Natural
Subcellular location ER
Secretion efficiency NA
Type Sec/SPI
Structure Information
PDB ID 8EOR,
Predicted Structure ID SPKB02986.cif
Physicochemical Information
Molecular weight 1908.29144
Aliphatic index 121.1764706
Isoelectric point 10.55000222
Charge (pH=7) 0.997980988
Topological polar surface area 683.09
Aromaticity 0.176470588
Average rotatable bonds 3.352941176
Number of hydrogen bond donors 26
Number of hydrogen bond acceptors 23
X logP energy -2.48853
Hydropathy 
Literature Information
Title Purification and characterization of a human liver cocaine carboxylesterase that catalyzes the production of benzoylecgonine and the formation of cocaethylene from alcohol and cocaine.
DOI 10.1016/0006-2952(94)90461-8,
Publication Year 1994
PubMed ID 7980644,
Patent ID NA,
