SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB02980

Signal sequence   MLPLCLVAALLLAAGPGPSLG

Length  21

Organism  Homo sapiens (Human)

UniProt ID  P22692,

Motif  1..21



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB02980.cif

Structure  SPKB02980.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  1977.49424

Aliphatic index  162.8571429

Isoelectric point  5.922539791

Charge (pH=7)   -0.063990417

Topological polar surface area  639.18

Aromaticity  0

Average rotatable bonds  2.761904762

Number of hydrogen bond donors  21

Number of hydrogen bond acceptors  25

X logP energy  -2.7594

Hydropathy 



Literature Information


Title  Identification and molecular cloning of two new 30-kDa insulin-like growth factor binding proteins isolated from adult human serum.

DOI  NA,

Publication Year  1991

PubMed ID  1709161,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.