SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB02974

Signal sequence   MVSKSLFLAAAVNLAGVLA

Length  19

Organism  Geotrichum candidum (Oospora lactis) (Dipodascus geotrichum)

UniProt ID  P22394,

Motif  1..19



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB02974.cif

Structure  SPKB02974.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  1875.30004

Aliphatic index  154.2105263

Isoelectric point  9.700002532

Charge (pH=7)   0.997689266

Topological polar surface area  696.69

Aromaticity  0.052631579

Average rotatable bonds  3.210526316

Number of hydrogen bond donors  24

Number of hydrogen bond acceptors  25

X logP energy  -5.0072

Hydropathy 



Literature Information


Title  Separation and characterization of two molecular forms of Geotrichum candidum lipase.

DOI  10.1093/oxfordjournals.jbchem.a123061,

Publication Year  1990

PubMed ID  2341377,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.