SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB02973

Signal sequence   MDYFPVIFSLLFVAFQGAPETAVLG

Length  25

Organism  Rattus norvegicus (Rat)

UniProt ID  P22388,

Motif  1..25



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB02973.cif

Structure  SPKB02973.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2733.21734

Aliphatic index  109.2

Isoelectric point  3.550073361

Charge (pH=7)   -2.000644508

Topological polar surface area  922.52

Aromaticity  0.2

Average rotatable bonds  3.24

Number of hydrogen bond donors  30

Number of hydrogen bond acceptors  33

X logP energy  -2.8289

Hydropathy 



Literature Information


Title  Peptidomics for Studying Limited Proteolysis.

DOI  10.1021/acs.jproteome.5b00820,

Publication Year  2015

PubMed ID  26479776,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.