General Information
SPKB ID SPKB02972
Signal sequence MQIITTALVCLLLAGMWPEDVDS
Length 23
Organism Homo sapiens (Human)
UniProt ID P22362,
Motif 1..23
Activity Information
Pathway SRP-dependent
Natural/Artificial Natural
Subcellular location ER
Secretion efficiency NA
Type Sec/SPI
Structure Information
PDB ID NA,
Predicted Structure ID SPKB02972.cif
Physicochemical Information
Molecular weight 2520.01204
Aliphatic index 135.6521739
Isoelectric point 3.380025655
Charge (pH=7) -3.061322325
Topological polar surface area 926.2
Aromaticity 0.043478261
Average rotatable bonds 3.47826087
Number of hydrogen bond donors 32
Number of hydrogen bond acceptors 34
X logP energy -5.1765
Hydropathy
Literature Information
Title Signal peptide prediction based on analysis of experimentally verified cleavage sites.
DOI 10.1110/ps.04682504,
Publication Year 2004
PubMed ID 15340161,
Patent ID NA,