General Information
SPKB ID SPKB02971
Signal sequence MHSSALLCCLVLLTGVRA
Length 18
Organism Homo sapiens (Human)
UniProt ID P22301,
Motif 1..18
Activity Information
Pathway SRP-dependent
Natural/Artificial Natural
Subcellular location ER
Secretion efficiency NA
Type Sec/SPI
Structure Information
PDB ID 7DF4,
Predicted Structure ID SPKB02971.cif
Physicochemical Information
Molecular weight 1887.34724
Aliphatic index 151.6666667
Isoelectric point 8.242951845
Charge (pH=7) 0.964940647
Topological polar surface area 709.29
Aromaticity 0
Average rotatable bonds 3.388888889
Number of hydrogen bond donors 28
Number of hydrogen bond acceptors 27
X logP energy -5.93923
Hydropathy
Literature Information
Title Signal peptide prediction based on analysis of experimentally verified cleavage sites.
DOI 10.1110/ps.04682504,
Publication Year 2004
PubMed ID 15340161,
Patent ID NA,