SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB02968

Signal sequence   MGTHARKKASLLLLVLATVALVSSPGWSFA

Length  30

Organism  Rattus norvegicus (Rat)

UniProt ID  P22063,

Motif  1..30



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB02968.cif

Structure  SPKB02968.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  3125.76614

Aliphatic index  123.6666667

Isoelectric point  11.82306209

Charge (pH=7)   3.088300011

Topological polar surface area  1178.22

Aromaticity  0.066666667

Average rotatable bonds  3.333333333

Number of hydrogen bond donors  43

Number of hydrogen bond acceptors  42

X logP energy  -9.49173

Hydropathy 



Literature Information


Title  The axonal glycoprotein TAG-1 is an immunoglobulin superfamily member with neurite outgrowth-promoting activity.

DOI  10.1016/0092-8674(90)90223-2,

Publication Year  1990

PubMed ID  2317872,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.