General Information
SPKB ID SPKB02967
Signal sequence MAALPMLWTGLVLLGLLGFPQTPA
Length 24
Organism Rattus norvegicus (Rat)
UniProt ID P22057,
Motif 1..24
Activity Information
Pathway SRP-dependent
Natural/Artificial Natural
Subcellular location ER
Secretion efficiency NA
Type Sec/SPI
Structure Information
PDB ID NA,
Predicted Structure ID SPKB02967.cif
Physicochemical Information
Molecular weight 2511.12174
Aliphatic index 138.3333333
Isoelectric point 6.099999998
Charge (pH=7) -0.002015701
Topological polar surface area 805.59
Aromaticity 0.083333333
Average rotatable bonds 3.083333333
Number of hydrogen bond donors 26
Number of hydrogen bond acceptors 30
X logP energy -1.5001
Hydropathy 
Literature Information
Title Structural and functional significance of cysteine residues of glutathione-independent prostaglandin D synthase. Identification of Cys65 as an essential thiol.
Publication Year 1995
PubMed ID 7836410,
Patent ID NA,
