SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB02966

Signal sequence   MQVSRVLAALCGMLLCASGLFA

Length  22

Organism  Mus musculus (Mouse)

UniProt ID  P21956,

Motif  1..22



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB02966.cif

Structure  SPKB02966.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2254.81044

Aliphatic index  133.1818182

Isoelectric point  8.231408964

Charge (pH=7)   0.874031556

Topological polar surface area  819.87

Aromaticity  0.045454545

Average rotatable bonds  3.363636364

Number of hydrogen bond donors  31

Number of hydrogen bond acceptors  31

X logP energy  -6.41413

Hydropathy 



Literature Information


Title  cDNA cloning of a mouse mammary epithelial cell surface protein reveals the existence of epidermal growth factor-like domains linked to factor VIII-like sequences.

DOI  10.1073/pnas.87.21.8417,

Publication Year  1990

PubMed ID  2122462,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.