SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB02964

Signal sequence   MQTPQYLQQRRKFAAAFLAFIFILAAVDTAEA

Length  32

Organism  Bos taurus (Bovine)

UniProt ID  P21782,

Motif  1..32



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB02964.cif

Structure  SPKB02964.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  3631.25314

Aliphatic index  95

Isoelectric point  9.296419389

Charge (pH=7)   0.999053836

Topological polar surface area  1414.1

Aromaticity  0.15625

Average rotatable bonds  3.65625

Number of hydrogen bond donors  48

Number of hydrogen bond acceptors  46

X logP energy  -9.53016

Hydropathy 



Literature Information


Title  Structural and functional characterization of full-length heparin-binding growth associated molecule.

DOI  10.1091/mbc.3.1.85,

Publication Year  1992

PubMed ID  1550956,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.